How does UV-C light work as a sanitizer?

UV-C light works on a physical level. Microorganisms like bacteria and viruses are rendered inactive by UV-C lights because of the way the light damages the nucleic acids of the cells. UV-C light has short wavelengths and high energy, which microorganism RNA and DNA absorb and by which they are destroyed, left unable to infect. 

Any scientific reference/research supporting UV-C works?

Yes, scientific and anecdotal references abound for UV-C’s efficacy both in literature and in reports of field applications. Of the government reports, NIOSH, OSHA, CDC, GSA, EPA are the most notable. Science in the public forum comes from the University of Cincinnati, Tulsa University, University of Colorado, and McGill University (Canada) to name a few. The two labs conducting independent testing and showing very favorable results are ARTI and Battelle. The list of prestigious field studies is too numerous to mention. UVC is used worldwide, more in other countries per capita than in the US. Much of this broader use is for the disinfection of drinking water and treatment of sewage in wastewater treatment.

Is UV-C light harmful to human skin and eye?

UV-C – includes the germicidal wavelength of 253.7nm and is used for air and water disinfection. Human overexposure causes temporary skin redness and harsh eye irritation, but no permanent damage, skin cancer, or cataracts.